Spider-Man 2 Boss FAQ Codes -

How to beat enemies:
To defeat enemies that block your attacks, have guns, or dodge your web, use the Web Splash maneuver (L2 + Triangle). This will quickly cover them up with webbing and will make them easier to defeat.

When trying to defeat enemies up on a roof top, just grapple one of them. When you have grappled a person, go to the edge of the wall and fully charge your jump, when you jump up to the highest you can, press the (x) button. This will make Spider-man kick them and let go of them, then the enemy will fall to his/her death. (this might not always kill them)

To defeat enemies easily, just throw them off a high building. Use an easy combo such as L1 + Square, then Charge Jump and press Square repeatedly, or just use L1 + Square frequently.